INSTITUTE FOR SYSTEMS BIOLOGY Charity Report

Public IRS 990 nonprofit record

INSTITUTE FOR SYSTEMS BIOLOGY

EIN 91-2003593 · Science & Technology (U500)

What they do

NON-PROFIT RESEARCH INSTITUTE to ADVANCE A SYSTEMS (OR HOLISTIC and CROSS-DISCIPLINARY) APPROACH to SCIENCE; PERSONALIZED MEDICINE; GLOBAL HEALTH & ENVIRONMENTAL SUSTAINABILITY; SCIENCE EDUCATION; & THE PIONEERING & INVENTION of BIOLOGICAL & TECHNOLOGICAL METHODS & TOOLS.

Before you give

Should I give to this charity?

Easy charity check

Look at where the money went

Of every $100 spent, about $71.10 was reported for mission work. Use the spending picture below and ask what results that work produced.

Plain answer: A tax form cannot prove that a charity is doing good. It can show how the charity says it spent its money—and point out questions you should ask.

Basic facts we verified

IRS warning checkNo IRS revocation warning appears in this data.

Money report from 2024The charity has a recent tax report to read.

They explain their jobThe charity tells us what it is trying to do.

They name their leaders26 people are listed in the latest report.

You can reach themThey list contact information, so you can ask questions.

Money made simple

80.04%of revenue went to mission work71.1% of expenses · Program services

1.02%of revenue went to fundraising0.9% of expenses

$112.53spent for every $100 of revenueSpending was higher than revenue this year.

31.47%of revenue went to management and office costs28.0% of expenses

$2.30in assets for every $1 spent this yearSome assets cannot be spent right away.

89.6%of its money came from giftsOther money may come from services or investments.

Ask these three easy questions

Who did you help? Ask for a recent story or report that shows real results.
What will my money do? Ask exactly what your gift will pay for.
Is this really the charity? Give only through its official website or confirmed phone number.

Worth asking: Expenses exceeded revenue by $5,294,963 this year. Ask whether that was planned or caused by a one-time event.

Pay context: The highest compensation shown in this filing is $565,815 for JAMES R HEATH PHD (PRESIDENT/PROFESSOR). Compare pay with organizations of similar size and complexity.

Bottom line: Do not decide from a name, mission statement, or tax status alone. Look at where the money went, then ask what changed, who was helped, and what your gift will do. YouCanGiveBack does not endorse or grade organizations.

Money

Financial picture

Tax year 2024

A plain-language look at the latest Form 990 figures available. These numbers help you ask better questions; they do not, by themselves, rate whether a charity is good or bad.

$100revenue

How each $100 of revenue was used

The large number compares each expense with revenue. The smaller number shows its share of total expenses.

Total reported revenue$42,255,091

Mission workProgram services$33,822,66980.04% of revenue71.1% of expenses

ManagementOffice and general costs$13,295,84331.47% of revenue28.0% of expenses

FundraisingAsking for donations$431,5421.02% of revenue0.9% of expenses

Total expenses$47,550,054112.53% of revenue

Expenses were greater than revenue, so the colored ring fills the available $100 and the total above 100% is shown below.

Has the pattern changed?

Colored bars = expense mix: how each year’s expenses were divided. Total expenses vs. revenue shows whether the charity spent less or more than it received. The current filing is first.

YearExpense mixDetails

2024CurrentExpense mix: 71.1% mission · 28.0% management · 0.9% fundraisingTotal expenses: 112.53% of revenue

2023Expense mix: 72.1% mission · 26.9% management · 1.0% fundraisingTotal expenses: 107.20% of revenue

2022Expense mix: 71.0% mission · 28.3% management · 0.8% fundraisingTotal expenses: 113.21% of revenue

2021Expense mix: 71.1% mission · 28.1% management · 0.8% fundraisingTotal expenses: 89.89% of revenue

2020Expense mix: 67.7% mission · 31.5% management · 0.8% fundraisingTotal expenses: 101.67% of revenue

2019Expense mix: 71.0% mission · 28.2% management · 0.8% fundraisingTotal expenses: 113.21% of revenue

2018Expense mix: 66.9% mission · 32.2% management · 0.8% fundraisingTotal expenses: 106.00% of revenue

2017Expense mix: 67.2% mission · 32.3% management · 0.5% fundraisingTotal expenses: 102.01% of revenue

Money in and money out

Revenue$42,255,091

Expenses$47,550,054

Annual shortfall $5,294,963 Expenses were higher than revenue for this filing year.

Reported spending amounts

Mission work means the Form 990 category called program services. These are reported accounting categories—not an independent measurement of results.

Mission work (program services)$33,822,669 · 71.1% of expenses

Management and office costs$13,295,843 · 28.0% of expenses

Fundraising$431,542 · 0.9% of expenses

See all reported dollar amounts

Revenue$42,255,091

Expenses$47,550,054

Assets$109,279,173

Income$55,889,322

Contributions$37,859,571

Mission work (program services)$33,822,669

Fundraising$431,542

Management and general$13,295,843

Stocks and bonds$53,524,742

Accounting fees$108,200

Investing fees$267,316

People

Leadership and board

Tax year 2024

Names, titles, time, and compensation below are reported by the organization on its Form 990.

People reported as paid

Person and titleCompensation

JAMES R HEATH PHDPRESIDENT/PROFESSOR · 55 hrs/week $565,815Base $509,772 · Other $56,043

NITIN BALIGA PHDSVP DIR OF INTEGRATIVE SCIENCE/PROF · 55 hrs/week $407,040Base $343,731 · Other $63,309

KATHY SCANLANCOO/TREASURER · 55 hrs/week $384,719Base $323,595 · Other $61,124

ANDREW MAGISDIRECTOR OF DATA SCIENCE · 50 hrs/week $326,585Base $282,804 · Other $43,781

ROBERT L MORTIZ PHDPROFESSOR · 50 hrs/week $312,980Base $271,421 · Other $41,559

SUI HUANG MD PHDPROFESSOR · 50 hrs/week $288,315Base $237,123 · Other $51,192

ERIKA KREGERDIRECTOR OF DEVELOPMENT · 50 hrs/week $248,911Base $186,033 · Other $62,878

ARI ROBICSEK MDDIRECTOR $215,815Base · Other $215,815

NAEHA SUBRAMANIAN PHDASSOCIATE PROFESSOR · 50 hrs/week $209,744Base $181,654 · Other $28,090

LEROY HOOD MD PHDDIRECTOR · 50 hrs/week $193,125Base $187,500 · Other $5,625

JIM MARTINDIRECTOR - THRU 6/24 $96,888Base · Other $96,888

HODA ASMAR MDDIRECTOR (PART YEAR) $22,605Base · Other $22,605

Compensation alone does not tell whether pay is reasonable. Consider the charity’s size, work, location, and results.

See everyone listed on the board or leadership roster (26)

JAMES R HEATH PHDPRESIDENT/PROFESSOR

NITIN BALIGA PHDSVP DIR OF INTEGRATIVE SCIENCE/PROF

KATHY SCANLANCOO/TREASURER

ANDREW MAGISDIRECTOR OF DATA SCIENCE

ROBERT L MORTIZ PHDPROFESSOR

SUI HUANG MD PHDPROFESSOR

ERIKA KREGERDIRECTOR OF DEVELOPMENT

ARI ROBICSEK MDDIRECTOR

NAEHA SUBRAMANIAN PHDASSOCIATE PROFESSOR

LEROY HOOD MD PHDDIRECTOR

JIM MARTINDIRECTOR - THRU 6/24

HODA ASMAR MDDIRECTOR (PART YEAR)

WASIF RASHEEDDIRECTOR - THRU 3/24

HEATHER REDMANDIRECTOR

AMY COMPTON-PHILLIPS MDDIRECTOR

JOHN SABEYDIRECTOR (PART YEAR)

DOUGLAS HOWEDIRECTOR

DAVID SABEYDIRECTOR

MELANIE L MAYER PHDDIRECTOR

DANIEL T LINGDIRECTOR

NANCY ALLBRITTON MD PHDDIRECTOR

CRAIG MUNDIEDIRECTOR

CHARLES WATTS MDBOARD CHAIR

ROGER PERLMUTTER MD PHDDIRECTOR

BRIAN V TURNERDIRECTOR

THOMAS J CABLEDIRECTOR

About this charity

Recognized since: January 2000
Location: 401 TERRY AVE N, SEATTLE, WA 98109-5263
County: King
In care of: % GARY C STREICHER
Primary officer: KATHY SCANLAN, COO/TREASURER

How to reach them

WebsiteVisit the charity’s website Phone(206) 732-1200

Filing and classification

Latest tax year: 2024
Tax period began: January 1, 2024
Return type: 990
Tax preparer: ERNST & YOUNG US LLP
NTEE classification: Science & Technology (U500)